The school closures in spring 2020 had a negative effect on the health and well-being of many young people. But homeschooling also had a positive flipside: Thanks to sleeping longer in the morning, many teenagers reported improved health and health-related quality of life. The study authors from the University of Zurich therefore believe school days should begin later in the morning.

Children are the highest consumers of added sugar, even as high-sugar diets have been linked to health effects like obesity and heart disease and even impaired memory function.

However, less is known about how high sugar consumption during childhood affects the development of the brain, specifically a region known to be critically important for learning and memory called the hippocampus.

New research led by a University of Georgia faculty member in collaboration with a University of Southern California research group has shown in a rodent model that daily consumption of sugar-sweetened beverages during adolescence impairs performance on a learning and memory task during adulthood. The group further showed that changes in the bacteria in the gut may be the key to the sugar-induced memory impairment.

Read More
Jan 5 • Updated on January 6, 2022 7:38 am • Edit History (1)

To be part of trucking industry is not an easy task.You need follow many rules and keep yourself updated to avoid any kind of safety breach.DOT compliance group is a Third party administrator who provide drug and alcohol testing in various conditions.

Dec 30, 2021

In a double-blind controlled study, high doses of magnetic brain stimulation, given on an accelerated timeline and individually targeted, caused remission in 79% of trial participants with severe depression.

Oct 25, 2021

The COVID-19 pandemic propelled many employees into remote work arrangements, and face-to-face meetings were quickly replaced with virtual meetings. This rapid uptick in the use of virtual meetings led to much popular press discussion of virtual meeting fatigue (i.e., “Zoom fatigue”), described as a feeling of being drained and lacking energy following a day of virtual meetings. In this study, we aimed to better understand how one salient feature of virtual meetings—the camera—impacts fatigue, which may affect outcomes during meetings (e.g., participant voice and engagement). We did so through the use of a 4-week within-person experience sampling field experiment where camera use was manipulated. Drawing from theory related to self-presentation, we propose and test a model where study condition (camera on versus off) was linked to daily feelings of fatigue; daily fatigue, in turn, was presumed to relate negatively to voice and engagement during virtual meetings. We further predict that gender and organizational tenure will moderate this relationship such that using a camera during virtual meetings will be more fatiguing for women and newer members of the organization. Results of 1,408 daily observations from 103 employees supported our proposed model, with supplemental analyses suggesting that fatigue affects same-day and next-day meeting performance. Given the anticipated prevalence of remote work even after the pandemic subsides, our study offers key insights for ongoing organizational best practices surrounding virtual meetings.

Read More
Aug 3, 2021

A healthy diet is about much more than calories: we need a wide range of nutrient-dense foods to get all of the vitamins and minerals that are essential for good health. In this post I look at the costs of diets around the world. Healthy diets are expensive; more than four times the cost of a basic, calorie-sufficient one. This is true in every country in the world. As a result, three billion people cannot afford a healthy diet, even if they spend most of their income on food.

Jul 24, 2021

That morning cup of joe may be just what you need to help jumpstart your workday and sharpen your mind. But if you find yourself repeatedly heading over to the coffee pot for refills, you may be actually putting your brain health at risk. Too much coffee can increase the risk of dementia, warns a new study.

Drinking six or more cups a day was linked with a 53 percent increased risk of dementia and make stroke more likely, too. Brain imaging reveals that drinking a lot of coffee was also associated with brain shrinkage, say scientists.

Read More
Jul 5, 2021

When people undergo a great trauma or other unsettling event—they have lost a job or a loved one dies, for example—their understanding of themselves or of their place in the world often disintegrates, and they temporarily “fall apart,” experiencing a type of depression referred to as existential depression. Their ordeal highlights for them the transient nature of life and the lack of control that we have over so many events, and it raises questions about the meaning of our lives and our behaviors. For other people, the experience of existential depression seemingly arises spontaneously; it stems from their own perception of life, their thoughts about the world and their place in it, as well as the meaning of their life. While not universal, the experience of existential depression can challenge an individual’s very survival and represents both a great challenge and at the same time an opportunity—an opportunity to seize control over one’s life and turn the experience into a positive life lesson—an experience leading to personality growth.

Read More

Antibody Contract Manufacturing Market is estimated to be worth USD 17 billion in 2030, predicts Roots Analysis

 

The benefits of engaging a CMO or CDMO for antibody development and production extend beyond fulfilling the needs of small companies; access to new technologies and operational flexibility are attractive attributes to larger players as well

 

Roots Analysis is pleased to announce the publication of its recent study, titled, “Antibody Contract Manufacturing Market, 2020-2030” report to its list of offerings.

The report features an extensive study of the current market landscape and future opportunities associated with the contract manufacturing of antibodies. The study also features a detailed analysis of key drivers and trends related to this evolving domain. In addition to other elements, the study includes:

·        A detailed review of the overall landscape of companies, offering contract services for the manufacturing of antibodies.

·        A competitiveness analysis of key players engaged in this domain, featuring an assessment based on their supplier strength and service strength.

·        A benchmark analysis, highlighting the key focus areas of small, mid-sized and large companies, comparing their existing capabilities within and beyond their respective (geography-based) peer groups.

·        An analysis of the various partnerships pertaining to contract manufacturing of antibodies, which have been established since 2013.

·        An analysis of the various expansion initiatives undertaken by service providers, in order to augment their respective antibody manufacturing capabilities, over the period 2017-2019 (till October).

·        An estimate of the overall, installed capacity for manufacturing antibodies based on data reported by industry stakeholders in the public domain.

·        Informed estimates of the annual commercial and clinical demand for antibodies, based on various relevant parameters, such as target patient population, dosing frequency and dose strength.

·        Elaborate profiles of the key industry players that offer contract manufacturing services at all scales of operation and have more than two manufacturing facilities.

·        A case study comparing the key characteristics of large molecule and small molecule drugs, along with details on the various steps and challenges involved in their respective manufacturing processes.

·        A discussion on affiliated trends, key drivers and challenges, under a SWOT framework, which are likely to impact the industry’s evolution.

Request for Latest Market Insights:

https://www.rootsanalysis.com/reports/view_document/antibody-cmo-market/295.html

A detailed market forecast, featuring analysis of the current and projected future opportunity across key market segments (listed below)

Type of Antibodies

·        Monoclonal Antibodies

·        Bispecific Antibodies

·        ADCs

·        Others

Company Size

·        Small

·        Mid-sized

·        Large / Very Large

Scale of Operation

·        Preclinical / Clinical

·        Commercial

Type of expression system used

·        Mammalian

·        Microbial

Key geographical regions

·        North America

·        Europe

·        Asia and RoW

Transcripts of interviews held with the following senior level representatives of stakeholder companies:

·        Dietmar Katinger (Chief Executive Officer, Polymun Scientific)

·        David C Cunningham (Director, Corporate Development, Goodwin Biotechnology)

·        Claire Otjes (Marketing Manager, Batavia Biosciences)

Market Key Players:

·        AGC Biologics

·        Aldevron

·        AMRI

·        Boehringer Ingelheim BioXcellence

·        Emergent BioSolutions

·        Eurofins CDMO

·        FUJIFILM Diosynth Biotechnologies

·        KBI Biopharma

·        Lonza

·        Nitto Avecia Pharma Services

·        Novasep

·        Pierre Fabre

·        Samsung BioLogics

·        Synthon

·        Thermo Fisher Scientific

For more information, please click on the following link:

https://www.rootsanalysis.com/reports/295/request-customization.html

Read More
Jun 24, 2021

Legend has it that Marie Antoinette’s hair turned gray overnight just before her beheading in 1791.

Though the legend is inaccurate—hair that has already grown out of the follicle does not change color—a new study(link is external and opens in a new window) from researchers at Columbia University Vagelos College of Physicians and Surgeons is the first to offer quantitative evidence linking psychological stress to graying hair in people.

And while it may seem intuitive that stress can accelerate graying, the researchers were surprised to discover that hair color can be restored when stress is eliminated, a finding that contrasts with a recent study in mice that suggested that stressed-induced gray hairs are permanent.

Read More
Jun 9, 2021

In a study of healthy volunteers, National Institutes of Health researchers have mapped out the brain activity that flows when we learn a new skill, such as playing a new song on the piano, and discovered why taking short breaks from practice is a key to learning. The researchers found that during rest the volunteers’ brains rapidly and repeatedly replayed faster versions of the activity seen while they practiced typing a code. The more a volunteer replayed the activity the better they performed during subsequent practice sessions, suggesting rest strengthened memories.

Read More
Jun 7, 2021

Psilocybin, the active compound in magic mushrooms, may be at least as effective as selective serotonin reuptake inhibitors, the leading type of antidepressant medication, according to research published in the New England Journal of Medicine. The phase 2, double-blind, randomized, controlled trial compared psilocybin to the antidepressant medication escitalopram.

“Our previous research in treatment-resistant depression and as well as human brain scanning strongly suggested the therapeutic potential of psilocybin. Pitting psilocybin in a head to head versus a conventional antidepressant felt like a brave and interesting test to do,” said study author Robin Carhart-Harris, the head of the Centre for Psychedelic Research at Imperial College London and founder of MyDelica.

The researchers recruited 59 men and women between the ages of 18 and 80 years who suffered from moderate-to-severe depression for their 6-week trial. Thirty patients were randomly assigned to the psilocybin group, while the remaining 29 patients were assigned to the escitalopram group.

Read More
Jun 5, 2021

Ultra-processed foods have known negative implications for health; however, their effect on skeletal development has never been explored. Here, we show that young rats fed ultra-processed food rich in fat and sugar suffer from growth retardation due to lesions in their tibial growth plates. The bone mineral density decreases significantly, and the structural parameters of the bone deteriorate, presenting a sieve-like appearance in the cortices and poor trabecular parameters in long bones and vertebrae. This results in inferior mechanical performance of the entire bone with a high fracture risk. RNA sequence analysis of the growth plates demonstrated an imbalance in extracellular matrix formation and degradation and impairment of proliferation, differentiation and mineralization processes. Our findings highlight, for the first time, the severe impact of consuming ultra-processed foods on the growing skeleton. This pathology extends far beyond that explained by the known metabolic effects, highlighting bone as a new target for studies of modern diets.

Read More
Jun 2, 2021

Mind-altering drugs such as psilocybin and MDMA could transform the treatment paradigm for mental health disorders, says neuroscientist David Nutt. But trial design considerations, regulatory hurdles and economics still pose problems for psychedelic-assisted therapies.

May 31, 2021

Fear of psychiatric hospitalization is one of the primary reasons that older men — an age and gender group at high risk for suicide — don’t talk about suicide with their physicians.

Researchers discovered this finding as part of a pre-launch, stakeholder assessment of a multimedia program designed to encourage men to open up to their primary care providers about suicidal thoughts. Called MAPS, for Men and Providers Preventing Suicide, the program will eventually be integrated into doctors’ office waiting areas.

The MAPS assessment was led by Anthony Jerant, chair of family and community medicine at UC Davis Health, and is published in the journal Patient Education and Counseling.

“Our overall goal is to initiate comfortable conversations with men about mental health and its treatment in outpatient primary care settings,” Jerant said. “Fear of hospitalization wasn’t really on our radar, proving that stakeholder interviews are crucial to shaping the development of suicide-prevention interventions like ours.”

Read More
health
Created on Jun 17, 2020
By @gurlic