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dmje responded to a post by John Titor
Dec 28, 2020

@johntitor So much interesting research in this area. Pollens’ book “How to change your mind” is pretty compelling and gives lots of examples of how psychedelics can be used in medical contexts.

What’s really interesting in my opinion is that there’s evidence that the changes they see aren’t chemical but more around pushing boundaries about what that patient believes. Here’s an extract from “Entangled Life” by Merlin Sheldrake:

“Similarly, in a study of psilocybin and tobacco addiction, the patients with the best results were those who had undergone the most powerful mystical experiences. Psilocybin appears to take effect not by pushing a set of biochemical buttons, but by opening patients’ minds to new ways of thinking about their lives and behaviours.”

Research into terminally ill patients who are given psilocybin seems to show that the barrier dropping and handing off of the previous sense of “self” is what makes a profound impact.

I’m personally interested in the @Mindfulness angle here. When covid is better I’m aiming for a psychedelic retreat :-)



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Combining the psychedelic drug psilocybin with supportive psychotherapy results in substantial rapid and enduring antidepressant effects among patients with major depressive disorder, according to a new randomized clinical trial. The findings have been published in JAMA Psychiatry.

The new study provides more evidence that psilocybin, a compound found in so-called magic mushrooms, can be a helpful tool in the treatment of psychiatric conditions.

“Prior studies in cancer patients and in an uncontrolled clinical trial in depressed patients using psilocybin-assisted therapy showed promising results. Because there had not been a control group those prior studies were limited,” said study author Alan K Davis, an assistant professor at Ohio State University and adjunct assistant professor at Johns Hopkins University.

“We were interested in testing whether psilocybin-assisted therapy would be helpful for people with depression because depression is one of the most prevalent and debilitating conditions in the world.”

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Thoughts about living mindfully
Created on Dec 23, 2020
By @dmje